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DNase I (Lyo)

CAT: 0980-LYE127-01Size: 100 UDry Ice: NoHazardous: No
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CAT#:0980-LYE127-01Size:100 U
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNase I is an endonuclease that can randomly degrade single stranded or double stranded DNA with equal efficiency to release di-, tri- and oligonucleotide products with 5´-phosphorylated and 3´-hydroxylated ends. DNase I acts on single- and double-stranded DNA, chromatin and RNA:DNA hybrids. The bioactivity of DNase I is highly dependent on Ca2+, Mg2+ or Mn2+. In the presence of Mg2+, DNase I cleaves each strand of dsDNA independently in a statistically random fashion. In the presence of Mn2+, the enzyme cleaves both DNA strands at approximately the same site, producing DNA fragments with blunt-ends or with overhang termini of only one or two nucleotides. DNase I (Lyo) is supplied as lyophilized powder.
Shipping Conditions
Ice Pack
Storage Conditions
2-8°C
Shelf Life
12 Months

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