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BDK-IN-1

CAT: 0804-HY-169334Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169334Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BDK-IN-1 (compound (-) -43) is a BDK inhibitor with the IC50 of 0.23 μM and the max inhibition of 90%. BDK-IN-1 decreases the level of phospho-E1 and can be used for study of cardiometabolic diseases[1].
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bdk-in-1.html
Smiles
O=C([C@@H]1[C@@](C2)([H])C=C[C@@]2([H])[C@H]1C(NC3=NC(C4=CC=C(F)C=C4F)=CS3)=O)O
Molecular Formula
C18H14F2N2O3S
Molecular Weight
376.38
References & Citations
[1]Liang J, et al. Bicyclic Inhibitors of Branched-Chain α-Keto Acid Dehydrogenase Kinase (BDK) with In Vivo Activity. ACS Med Chem Lett. 2024;15 (11) :1899-1906.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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