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Lexacalcitol

CAT: 0804-HY-32340-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-32340-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lexacalcitol (KH1060), a vitamin D analog, is a potent regulator of cell growth and immune responses. Lexacalcitol can be used for the research of graft rejection, psoriasis, cancer and auto-immune diseases[1][2].
CAS Number
131875-08-6
Product Name Alternative
KH1060
UNSPSC
12352211
Hazard Statement
H300
Target
VD/VDR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Lexacalcitol.html
Purity
99.42
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]1(CCC/2)[C@](CC[C@@H]1[C@@H](C)OCCCC(CC)(CC)O)([H])C2=C\C=C(C[C@@H](O)C[C@@H]3O)/C3=C
Molecular Formula
C29H48O4
Molecular Weight
460.69
Precautions
P264-P270-P330-P405-P501
References & Citations
[1]L Binderup, et al. 20-epi-vitamin D3 analogues: a novel class of potent regulators of cell growth and immune responses. Biochem Pharmacol. 1991 Sep 27;42 (8) :1569-75.|[2]C Gysemans, et al. A combination of KH1060, a vitamin D (3) analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic mice. Transplant Proc. 2001 May;33 (3) :2365.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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