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GBRT rabbit pAb

CAT: 0855-ES16225-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES16225-01Size:50 µL
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Background
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3) . [provided by RefSeq, Nov 2009]
Description
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3). [provided by RefSeq, Nov 2009],
UniProt
Q9UN88
Swiss Prot
Q9UN88
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human GBRT AA range: 317-367
Target
GBRT
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Gene ID (Human)
55879

UniProtKB · Q9UN88

Gamma-aminobutyric acid receptor subunit theta

GBRT_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UN88
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GABRQ
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A6NFN1, Q32MB4, Q9NZK8
Protein keywords

Cellular component

Cell membraneMembranePostsynaptic cell membraneSynapse

Ligand

Chloride

Molecular function

Chloride channelIon channel

PTM

Disulfide bondGlycoprotein

Biological process

Ion transportTransport

Technical term

Proteomics identificationReference proteome

Domain

SignalTransmembraneTransmembrane helix

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