Ampicillin-d5

• Description:

  Ampicillin-d5 is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H317, H319, H334, H335

• Target:

  Antibiotic; Bacterial

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Purity:

  99.4

• Solubility:

  10 mM in DMSO|H2O : 4.9mg/mL (ultrasonic; warming; adjust pH to 9 with NaOH; heat to 60°C)

• Smiles:

  O=C([C@@H](C1=C(C([2H])=C(C([2H])=C1[2H])[2H])[2H])N)N[C@@H]2C(N3[C@@]2(SC(C)([C@@H]3C(O)=O)C)[H])=O

• Molecular Formula:

  C16H14D5N3O4S

• Molecular Weight:

  354.44

• Precautions:

  H315, H317, H319, H334, H335

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Chopra SL, et al. Effect of Ampicillin on E. Coli of Swine Origin. Can J Comp Med Vet Sci. 1963 Sep;27 (9) :223-7.|[3]Lund B, et al. Ampicillin in portal and peripheral blood and bile after oral administration of ampicillin andpivampicillin. Eur J Clin Pharmacol. 1974;7 (2) :133-5.|[4]Lee KE, et al. The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia. Korean J Physiol Pharmacol. 2016 Mar;20 (2) :185-92.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• Isoform:

  β-lactam

• CAS Number:

  [1426173-65-0]