Ampicillin

• UNSPSC Description:

  Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

• Target Antigen:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Ampicillin.html

• Purity:

  99.92

• Solubility:

  H2O : 4.9 mg/mL (ultrasonic;warming;adjust pH to 9 with NaOH;heat to 60°C)

• Smiles:

  OC([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=CC=C3)N)=O)([H])SC1(C)C)=O

• Molecular Weight:

  349.40

• References & Citations:

  [1]Chopra SL, et al. Effect of Ampicillin on E. Coli of Swine Origin. Can J Comp Med Vet Sci. 1963 Sep;27(9):223-7.|[2]Lund B, et al. Ampicillin in portal and peripheral blood and bile after oral administration of ampicillin andpivampicillin. Eur J Clin Pharmacol. 1974;7(2):133-5.|[3]Lee KE, et al. The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia. Korean J Physiol Pharmacol. 2016 Mar;20(2):185-92.ACS Infect Dis. 2023 Nov 28.|Animal Diseases. 02 November 2021.|Aquaculture. 2021, 736248.|Biochem Pharmacol. 2024 Oct 23:116593.|Biomed Res Int. 2018 Jul 2;2018:3579832. |bioRxiv. 2024 May 10.|Cancer Immunol Res. 2022 Dec 2;10(12):1542-1558.|Cell Metab. 2023 Sep 29:S1550-4131(23)00340-6.|Cell Metab. 2024 Sep 28:S1550-4131(24)00366-8.|Chemosphere. 2023 Oct 3:344:140353.|Emerg Microbes Infect. 2022 Feb 22;1-34.|Front Aging Neurosci. 2022 Jul 28;14:858130.|Genome Biol. 2023 Apr 30;24(1):98.|Gut Microbes. 2023 Dec;15(2):2249143.|Gut Microbes. 2023 Dec;15(2):2282790.|Heliyon. 2024 Jun 06.|iScience. 2023 Mar.|iScience. 2023 Oct 5.|J Agric Food Chem. 2024 Apr 10.|J Antimicrob Chemother. 2023 Feb 13;dkad032.|J Antimicrob Chemother. 2024 Jul 13:dkae229.|J Antimicrob Chemother. 2024 Jul 20:dkae218.|J Cell Physiol. 2021 Dec 8.|J Pharm Anal. 2023 Jun 16.|Life Sci. 2020 Nov 15;261:118473.|Microbiol Spectr. 2022 Jan 12;e0099121.|Microorganisms. 2024 Mar 13, 12(3), 575.|mSystems. 2023 Dec 4:e0102623.|Nat Commun. 2022 Mar 2;13(1):1116.|Naunyn Schmiedebergs Arch Pharmacol. 2024 Oct 1.|Neural Regen Res. 2024 Sep 1;19(9):2081-2088.|Nutrients. 2023 Oct 18, 15(20), 4427.|Pharmacol Res. 2024 May 21:205:107229.|Res Sq. 2024 Oct 02.|Research Square Preprint. 2020 Jun.|Research Square Preprint. 2021 Feb.|SSRN. 2023 Sep 11.|Vet Microbiol. 2024 May, 292, 110046.|Vet Res Commun. 2024 Sep 26.|ACS Infect Dis. 2024 Jul 27.|ACS Omega. 2023 Mar 6.|Am J Chin Med. 2024 Aug 21:1-28.|Cell Rep Med. 2023 Dec 19;4(12):101340.|Emerg Microbes Infect. 2024 Dec;13(1):2321981.|Nucleic Acids Res. 2022 Dec 12;gkac1141.|Sci Adv. 2023 Feb 17;9(7):eade4770.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  Launched

• CAS Number:

  69-53-4