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DFHO

CAT: 0804-HY-136277-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136277-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells[1][2].
CAS Number
1420815-34-4
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dfho.html
Purity
99.83
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1C)/C(N=C1/C=N/O)=C\C(C=C2F)=CC(F)=C2O
Molecular Formula
C12H9F2N3O3
Molecular Weight
281.21
References & Citations
[1]Wenjiao Song, et al. Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex. Nat Chem Biol. 2017 Nov;13 (11) :1187-1194.|[2]Hyaeyeong Kim, et al. A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization. Cell Chem Biol. 2019 Dec 19;26 (12) :1725-1731.e6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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