Anthraflavic acid

• Description :

  Anthraflavic acid, a flavonoid, is a potent IQ mutagenicity inhibitor by virtue of its ability to inhibit both its microsomal and cytosolic activation pathways. Anthraflavic acid is a potent and specific cytochrome P-448 inhibitor activity an enzyme system closely associated with the activation of many chemical carcinogens[1].

• CAS Number :

  [84-60-6]

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  Cytochrome P450

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anthraflavic-acid.html

• Purity :

  99.51

• Solubility :

  DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C1C2=C(C=C(O)C=C2)C(C3=CC=C(O)C=C13)=O

• Molecular Formula :

  C14H8O4

• Molecular Weight :

  240.21

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Ayrton AD, et al. Anthraflavic acid inhibits the mutagenicity of the food mutagen IQ: mechanism of action. Mutat Res. 1988 Mar-Apr;207 (3-4) :121-5.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported