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Etoperidone (hydrochloride)

CAT: 0804-HY-106617ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106617ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Etoperidone hydrochloride, an antidepressant agent, is an orally active serotonin and nor-adrenaline re-uptake antagonist. Etoperidone hydrochloride shows Kd values of 36 nM, 38 nM, 85 nM, and 570 nM for 5-HT2 receptor, α1-adrenergic receptor, 5-HT1A receptor, and α2-adrenergic receptor, respectively[1][2].
CAS Number
57775-22-1
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/etoperidone-hydrochloride.html
Smiles
O=C1N(CCCN2CCN(CC2)C3=CC(Cl)=CC=C3)N=C(CC)N1CC.Cl
Molecular Formula
C19H29Cl2N5O
Molecular Weight
414.37
References & Citations
[1]G W Caldwell, et al. Evaluation of the absorption, excretion and metabolism of [14C] etoperidone in man. Xenobiotica. 2001 Nov;31 (11) :823-39. |[2]B Cusack, et al. Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl) . 1994 May;114 (4) :559-65.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3; α adrenergic receptor; α-1 microglobulin

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