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Ophiobolin B

CAT: 0804-HY-N6780-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6780-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ophiobolin B, a sesterterpene metabolite of Helminthosporium oryzae, inhibits proton extrusion from maize coleoptiles. Ophiobolin B inhibits fusicoccin (FC) promoted proton extrusion, potassium uptake and cell enlargement[1]. The MIC values with the antifungal effect of Ophiobolins B on different zygomycetes is 25–50 μg/mL[2].
CAS Number
5601-74-1
UNSPSC
12352211
Hazard Statement
H315-H319-H335
Target
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ophiobolin-b.html
Purity
99.53
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@@]12C[C@@]([C@@]3([H])/C(C=O)=C\C[C@@]1([H])[C@](CC2)([C@@H](C)CC/C=C(C)\C)O)([C@](C)(O)CC3=O)[H]
Molecular Formula
C25H38O4
Molecular Weight
402.57
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Gianani L, et al. Effects of ophiobolin B on cell enlargement and H (+) /K (+) exchange in maize coleoptile tissues. Planta. 1979 Jan;146 (3) :271-4.|[2]Krizsán K, et al. Effect of the sesterterpene-type metabolites, ophiobolins A and B, on zygomycetes fungi. FEMS Microbiol Lett. 2010 Dec;313 (2) :135-40.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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