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(S) -Renzapride

CAT: 0804-HY-14147A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14147A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -Renzapride ((S) -BRL 24924) is the isomer of HY-14147 Renzapride. Renzapride is a 5-HT4 receptor agonist with a Ki value of 115 nM. Renzapride also is a 5HT2b and 5HT3 receptor antagonist. Renzapride can be used for constipation predominant irritable bowel syndrome (C-IBS) study[1][2].
Product Name Alternative
(S) -BRL 24924
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s-renzapride.html
Purity
98.06
Solubility
DMSO : 35 mg/mL (ultrasonic)
Smiles
ClC1=C(N)C=C(OC)C(C(N[C@H]2CCN3CCC[C@H]2C3)=O)=C1
Molecular Formula
C16H22ClN3O2
Molecular Weight
323.82
References & Citations
[1]Camilleri M, et al. Effect of renzapride on transit in constipation-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol. 2004;2 (10) :895-904. |[2]Scarpellini E, et al. Renzapride: a new drug for the treatment of constipation in the irritable bowel syndrome. Expert Opin Investig Drugs. 2008;17 (11) :1663-1670.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor

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