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L-Quebrachitol

CAT: 0804-HY-N2375-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2375-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Quebrachitol is a methoxy analog of inositol that can be isolated from plants. L-Quebrachitol has free-radical scavenging, gastroprotection, anti-platelet aggregation and anti-diabetic activity. L-Quebrachitol promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway[1][2][3].
CAS Number
642-38-6
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
P38 MAPK; Wnt; β-catenin
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-quebrachitol.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
CO[C@H]1[C@@H]([C@H]([C@H](O)[C@H](O)[C@H]1O)O)O
Molecular Formula
C7H14O6
Molecular Weight
194.18
Precautions
H315, H319, H335
References & Citations
[1]Yodthong T, et al. l-Quebrachitol Promotes the Proliferation, Differentiation, and Mineralization of MC3T3-E1 Cells: Involvement of the BMP-2/Runx2/MAPK/Wnt/β-Catenin Signaling Pathway. Molecules. 2018 Nov 26;23 (12) .|[2]Li Y, et al. L-quebrachitol extracted from industrial rubber serum: a study on its antioxidant activities and bone mineral density enhancing functions[J]. Industrial Crops and Products, 2023, 201: 116943.|[3]Mu Y, et al. Sea buckthorn leaf l-quebrachitol extract for improved glucose and lipid metabolism in insulin resistant HepG2 Cells[J]. Bioresources, 2022, 17 (1) : 527.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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M20479-01L-quebrachitol
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A22312-10L-Quebrachitol 10mg
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