SEC61B Rabbit pAb

CAT: 0855-ES13170-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES13170-01Size:50 µL
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Background
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]
Description
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008],
Product Name Alternative
Protein transport protein Sec61 subunit beta
UniProt
P60468
Swiss Prot
P60468
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human SEC61B AA range: 30-110
Target
SEC61B
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA (peptide) 1:5000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass membrane protein .
Other Product Names
Protein transport protein Sec61 subunit beta
Gene ID (Human)
10952

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