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Recombinant Human Interleukin-17F

CAT: 0355-AP60012Size: InquireDry Ice: NoHazardous: No
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CAT#:0355-AP60012Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human Interleukin-17F (IL-17F) is encoded by the IL17F gene located on the chromosome 6 and belongs to the IL-17 family which contains IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F. IL-17F that shares 50 % homologous of crystal structure to IL-17A and is expressed by activated T cells, has the functions of stimulating production of other cytokines (such as IL-6, IL-8 and granulocyte colony-stimulating factor) and proliferation of PBMC and T-cell, regulating cartilage matrix turnover, and inhibiting angiogenesis.
Product Name Alternative
ML-1, IL-24
Gene ID
112744
UniProt
Q96PD4
Target
MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
Purification
> 95 % by SDS-PAGE and HPLC analyses.
Endotoxin
Less than 1 EU/ug of rHuIL-17F as determined by LAL method.
Bioactivity
4
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculated Molecular Weight
Approximately 30.1 kDa, a disulfide-linked homodimer of two 134 amino acid polypeptide chains.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Host or Source
Escherichia coli

UniProtKB · Q96PD4

Interleukin-17F

IL17F_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96PD4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL17F
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-17F
EC number
—
Processing
Precursor
Secondary accessions
Q6NSI0, Q7Z6P4, Q96PI8, Q9NUE6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Adaptive immunityImmunityInflammatory responseInnate immunity

Molecular function

Cytokine

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

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