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Recombinant Human Interleukin-20

CAT: 0355-AP60015Size: InquireDry Ice: NoHazardous: No
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CAT#:0355-AP60015Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human Interleukin-20 (IL-20) is encoded by the IL20 gene located on the chromosome 1 and belongs to the IL-10 family that including IL-10, IL-19, IL-22, IL-24, and IL-26. It is secreted by activated keratinocytes and monocytes, and signals through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 has functions of regulating proliferation and differentiation of keratinocytes during inflammation, and causing cell expansion of multipotential hematopoietic progenitor cells.
Product Name Alternative
Cytokine Zcyto10
Gene ID
50604
UniProt
Q9NYY1
Target
MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
Purification
> 95 % by SDS-PAGE and HPLC analyses.
Endotoxin
Less than 1 EU/ug of rHuIL-20 as determined by LAL method.
Bioactivity
6
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculated Molecular Weight
Approximately 17.6 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.2, with trehalose.
Host or Source
Escherichia coli

UniProtKB · Q9NYY1

Interleukin-20

IL20_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NYY1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL20
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-20
EC number
—
Processing
Precursor
Secondary accessions
Q17RB3, Q2THG6, Q96QZ6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Cytokine

PTM

Disulfide bond

Cellular component

Secreted

Domain

Signal

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