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1-NBX

CAT: 0804-HY-161418Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161418Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-NBX is a potent and selective A1R ligand. 1-NBX exhibits significantly improved A1R affinity with with a Ki of 2.6 nM and lower affinity for the A2A receptor with a Ki of 164 nM[1].
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/1-nbx.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N=C([C@]34CC[C@@H](C4)CC3)N2)N(CCCF)C(N1CCC)=O
Molecular Formula
C18H25FN4O2
Molecular Weight
348.42
References & Citations
[1]Swen Humpert, et al. 8-Bicycloalkyl-CPFPX derivatives as potent and selective tools for in vivo imaging of the A1 adenosine receptor. Eur J Med Chem. 2024 Apr 6:271:116380.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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