2'-Deoxycytidine-2'-13C

2'-Deoxycytidine-2'-13C

• UNSPSC Description: 2'-Deoxycytidine-2'-13C is 13C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer[1][2][3].
• Target Antigen: Endogenous Metabolite; Isotope-Labeled Compounds
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Others
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-deoxycytidine-2-13c.html
• Smiles: O[C@H]1[13CH2][C@H](N2C=CC(N)=NC2=O)O[C@@H]1CO
• Molecular Weight: 228.21
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Iwazaki A, et al. Intravenously administered 2'-deoxycytidine suppresses mouse myeloma tumor growth. Biol Pharm Bull. 2012;35(2):251-5.|[3]Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2(5):469-81.
• Shipping Conditions: Room temperature
• Clinical Information: Phase 3