ERK5-IN-1
CAT:
804-HY-14403-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ERK5-IN-1
- CAS Number: 1234479-76-5
- UNSPSC Description: ERK5-IN-1 is a potent ERK5 inhibitor with an IC50 of 87±7 nM. ERK5-IN-1 also inhibits LRRK2[G2019S] with an IC50 of 26 nM.
- Target Antigen: ERK
- Type: Reference compound
- Related Pathways: MAPK/ERK Pathway;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/ERK5-IN-1.html
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: O=C1C2=C(C=CC=C2)N(C)C3=NC(NC4=C(OC)C=C(N5CCN(C)CC5)C=C4)=NC=C3N1C
- Molecular Weight: 459.54
- References & Citations: [1]Deng X, et al. Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones. Eur J Med Chem. 2013;70:758-767.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported