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1,4-Cineole

CAT: 0804-HY-N7117-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7117-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1,4-Cineole is an oxygenated monoterpene found in eucalyptus oil. 1,4-Cineole is a hTRPM8 and hTRPA1 agonist. 1,4-Cineole can increase intracellular Ca2+ concentration. 1,4-Cineole exhibits anti-anxiety and anti-depression effects. 1,4-Cineole can be used for the research of neurological disease, such as depression [1][2].
CAS Number
470-67-7
UNSPSC
12352005
Hazard Statement
H225, H303
Target
TRP Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/1-4-cineole.html
Purity
95.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(C12CCC(O2)(C)CC1)C
Molecular Formula
C10H18O
Molecular Weight
154.25
Precautions
H225, H303
References & Citations
[1]Takaishi M, et al. 1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1. Mol Pain. 2012 Nov 29;8:86.|[2]Dougnon G, et al. Inhalation Administration of the Bicyclic Ethers 1,8- and 1,4-cineole Prevent Anxiety and Depressive-Like Behaviours in Mice. Molecules. 2020 Apr 18;25 (8) :1884.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
TRPA1; TRPM8

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