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GAP43 (Phospho-Ser41) Antibody

CAT: 0013-GTR18055887-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR18055887-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GAP43 encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene
UniProt
P17677
Reactivity
Human, Mouse, Rat
Target
The antibody detects endogenous level of GAP43 only when phosphorylated at Ser41
Clonality
Polyclonal
Conjugation
Unconjugated
Sequence
Peptide sequence around phosphorylation site of Ser41 (Q-A-S (p) -F-R) derived from Human GAP43
Field of Research
Neuroscience
Concentration
1mg/ml
Dilution
Immunofluorescence: 1:100 - 1:200
Purity
Purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Form
Supplied at 1.0mg/mL in phosphate-buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol
Molecular Weight
Predicted MW: 43kd
Storage Conditions
Store at -20°C for long term preservation (recommended) . Store at 4°C for short term use
Notes
For research use only.
Tested Applications
IF
Host or Source
Rabbit

UniProtKB · P17677

Neuromodulin

NEUM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17677
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GAP43
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K0Y4
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Calmodulin-bindingDevelopmental protein

Cellular component

Cell membraneCell projectionCytoplasmMembraneSynapse

Biological process

DifferentiationGrowth regulationNeurogenesis

PTM

LipoproteinPalmitatePhosphoprotein

Technical term

Proteomics identificationReference proteome

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