Products for Research Use Only

MTOR (Ab-2448) Antibody

CAT: 0013-GTR18056135-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR18056135-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MTOR (Ab-2448) Antibody
UniProt
P42345
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
References & Citations
Ankan Mitra 1, Ankur Das 1, Sourav Ghosh 1, Swaimanti Sarkar 1, Debasish Bandyopadhyay 1, Somnath Gangopadhyay 1, Sreya Chattopadhyay Metformin instigates cellular autophagy to ameliorate high-fat diet-induced pancreatic inflammation and fibrosis/EMT in mice Biochim Biophys Acta Mol Basis Dis, (2024), Mazumder, Arindam Ghosh et al. Mycophenolate mofetil contributes to downregulation of the hippocampal interleukin type 2 and 1β mediated PI3K/AKT/mTOR pathway hyperactivation and attenuates neurobehavioral comorbidities in a rat model of temporal lobe epilepsy Brain Behav Immun, 75, 84-93 (2019)
Pubmed id
38901652, 30243822
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IF, IHC, WB
Host or Source
Rabbit

UniProtKB · P42345

Serine/threonine-protein kinase mTOR

MTOR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P42345
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MTOR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmCytoplasmic vesicleEndoplasmic reticulumGolgi apparatusLysosomeMembraneMicrosomeMitochondrionMitochondrion outer membraneNucleus

Disease

Disease variantEpilepsyIntellectual disability

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

Domain

RepeatTPR repeat