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Mitiglinide (calcium hydrate) (Standard)

CAT: 0804-HY-B0682AR-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0682AR-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mitiglinide (calcium hydrate) (Standard) is the analytical standard of Mitiglinide (calcium hydrate) . This product is intended for research and analytical applications. Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel) . Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes[1][2].
CAS Number
207844-01-7
Product Name Alternative
KAD-1229 (Standard) ; S-21403 (Standard)
UNSPSC
12352005
Target
Potassium Channel; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mitiglinide-calcium-hydrate-standard.html
Smiles
O=C(N1C[C@@](CCCC2)([H])[C@@]2([H])C1)C[C@@H](C([O-])=O)CC3=CC=CC=C3.[0.5Ca2+].O
Molecular Formula
C19H24NO3.1/2Ca.H2O
Molecular Weight
352.46
References & Citations
[1]Y Sunaga, et al. The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide. Eur J Pharmacol. 2001 Nov 9;431 (1) :119-25.|[2]Kiyoshi Ichikawa, et al. Effect of KAD-1229, a novel hypoglycaemic agent, on plasma glucose levels after meal load in type 2 diabetic rats. Clin Exp Pharmacol Physiol. May-Jun 2002;29 (5-6) :423-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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