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Mitiglinide (calcium)

CAT: 0804-HY-17398-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-17398-01Size:100 mg
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Description
Mitiglinide Calcium (KAD-1229 anhydrous), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide Calcium is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel) . Mitiglinide Calcium can be used for the research of type 2 diabetes[1][2].
CAS Number
[145525-41-3]
Product Name Alternative
KAD-1229 (anhydrous) ; S21403 (anhydrous)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Mitiglinide-Calcium.html
Purity
98.82
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C([O-])[C@H](CC(N1C[C@](CCCC2)([H])[C@]2([H])C1)=O)CC3=CC=CC=C3.[0.5Ca2+]
Molecular Formula
C19H24NO3.1/2Ca
Molecular Weight
334.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Y Sunaga, et al. The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide. Eur J Pharmacol. 2001 Nov 9;431 (1) :119-25.|[2]Kiyoshi Ichikawa, et al. Effect of KAD-1229, a novel hypoglycaemic agent, on plasma glucose levels after meal load in type 2 diabetic rats. Clin Exp Pharmacol Physiol. May-Jun 2002;29 (5-6) :423-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

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