Anti-BoNT-A | Botulinum Neurotoxin A (Heavy Chain Binding Domain)

Anti-BoNT-A | Botulinum Neurotoxin A (Heavy Chain Binding Domain)

• Background: Botulinum toxinis a toxin produced by the anaerobic, gram-positive, bacterium of the genusClostridium(C. botulinum, C. butyricum, C. baratii and C. argentinense).These strains are widely distributed and can be found in soil and dust. Eight types of botulinum toxin are distinguished, named type A–H. Type A and B are capable of causing disease in humans (botulism) and have longest activity in vivo, and are also used commercially (BOTOX) and medically. Types C–G are less common; types E and F can cause disease in humans, while the other types cause disease in other animals. BotA is cleaved into two chains: heavy and light.Alternative name: Bontoxilysin-A
• CAS Number: 9007-83-4
• Host: Chicken
• Reactivity: Botulinum toxin A heavy chain
• Immunogen: Highly purified Botulinum Neurotoxin Type A (Heavy Chain Binding Domain) isolated fromClostridium botulinum.
• Clonality: Polyclonal
• Applications: ELISA (ELISA), Western blot (WB)
• Dilution: To be determined by the end user.
• Purity: Immunogen affinity purified in PBS pH 7.2 with 50 % glycerol and 0.1% 2-chloroacetamide
• Format: Liquid
• Molecular Weight: 97 kDa
• Storage Conditions: Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.