Acepromazine-OTs

• UNSPSC Description:

  Acepromazine-OTs is a cereblon (CRBN) ligand used in the recruitment of the cereblon (CRBN) protein. Acepromazine-OTs can be connected to the target protein ligand through a linker to form a PROTAC molecule, TrimTAC1 (HY-169355)[1].

• Target Antigen:

  Ligands for E3 Ligase

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/acepromazine-ots.html

• Smiles:

  CC(C1=CC2=C(C=C1)SC3=C(C=CC=C3)N2CCCOS(C4=CC=C(C=C4)C)(=O)=O)=O

• Molecular Weight:

  453.57

• References & Citations:

  [1]Panrui Lu, et al. Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell. 2024 Oct 30:S0092-8674(24)01197-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  102951-20-2