RNase H2

RNase H2

• UNSPSC Description: RNase H2 is the predominant source of RNase H activity in mammalian and human cells. RNase H2 protects genome integrity. RNase H2 has been associated with ribonucleotide removal from genomic DNA in yeast and mouse, where it is required for embryonic development[1][2].
• Target Antigen: Others
• Type: Enzyme
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/rnase-h2.html
• Solubility: 10 mM in DMSO
• Smiles: [RNase H2]
• References & Citations: [1]Feng S, Cao Z. Is the role of human RNase H2 restricted to its enzyme activity? Prog Biophys Mol Biol. 2016 May;121(1):66-73.|[2]Chon H, et al. RNase H2 roles in genome integrity revealed by unlinking its activities. Nucleic Acids Res. 2013 Mar 1;41(5):3130-43.
• Shipping Conditions: Blue Ice
• Storage Conditions: Store at -20°C for 2 years
• Clinical Information: No Development Reported