Products for Research Use Only

BACE rabbit pAb Antibody

CAT: 0013-GTR18051954-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR18051954-01Size:50 μL
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Description
Rabbit polyclonal antibody to BACE
Product Name Alternative
Anti-BACE1 antibody, anti-BACE antibody, anti-KIAA1149 antibody, anti-Beta-secretase 1 antibody, anti-Aspartyl protease 2 antibody, anti-ASP2 antibody, anti-Asp 2 antibody, anti-Beta-site amyloid precursor protein cleaving enzyme 1 antibody, anti-Beta-site APP cleaving enzyme 1 antibody, anti-Memapsin-2 antibody, anti-Membrane-associated aspar antibody
UniProt
P56817
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human BACE. AA range:452-501
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Rabbit
Field of Research
Cell Biology
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
56kD
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, IF, IHC
Preservative
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Isotype
IgG

UniProtKB · P56817

Beta-secretase 1

BACE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P56817
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BACE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.23.46
Processing
Precursor
Secondary accessions
A0M8W7, B0YIU9, E9PE65, H7BXJ9, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5, Q9ULS1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugationZymogen

Coding sequence diversity

Alternative splicing

Molecular function

Aspartyl proteaseHydrolaseProtease

Cellular component

Cell membraneCell projectionCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembrane

Domain

SignalTransmembraneTransmembrane helix