Amprolium (hydrochloride)

• UNSPSC Description:

  Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption[1][2][3][4].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Amprolium-hydrochloride.html

• Purity:

  99.15

• Solubility:

  H2O : ≥ 200 mg/mL

• Smiles:

  CC1=CC=CC=[N+]1CC2=CN=C(CCC)N=C2N.[Cl-].Cl

• Molecular Weight:

  315.24

• References & Citations:

  [1]Iqbal A, et al. Antiparasitic efficacy of Artemisia absinthium, toltrazuril and amprolium against intestinal coccidiosis in goats. J Parasit Dis. 2013 Apr;37(1):88-93.|[2]Lindsay DS, et al. Effects of sulfadiazine and amprolium on Neospora caninum (Protozoa: Apicomplexa) infections in mice. J Parasitol. 1990 Apr;76(2):177-9.|[3]Kennedy O Ogolla, et al. Efficacy of Sulphachloropyrazine, Amprolium Hydrochloride, Trimethoprim-Sulphamethoxazole, and Diclazuril against Experimental and Natural Rabbit Coccidiosis. J Vet Med. 2018 Oct 23:2018:5402469.|[4]G Rindi, et al. Action of Amprolium on the thiamine content of rat tissues. J Nutr. 1966 Jun;89(2):197-202.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  137-88-2