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Perillyl alcohol

CAT: 0804-HY-N7000-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7000-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Perillyl alcohol is an orally active monoterpene. Perillyl alcohol exhibits multiple activities such as analgesic, anti-inflammatory, anti-tumor, anti-angiogenic, and anti-nociceptive effects. Perillyl alcohol can induce apoptosis and cell cycle arrest in tumor cells[1][2][3][4].
CAS Number
536-59-4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Akt; Apoptosis; Caspase; Ras; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/perillyl-alcohol.html
Purity
95.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCC1=CCC(C(C)=C)CC1
Molecular Formula
C10H16O
Molecular Weight
152.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Loutrari H, et al. Perillyl alcohol is an angiogenesis inhibitor. J Pharmacol Exp Ther. 2004 Nov;311 (2) :568-75.|[2]Lluria-Prevatt M, et al. Effects of perillyl alcohol on melanoma in the TPras mouse model. Cancer Epidemiol Biomarkers Prev. 2002 Jun;11 (6) :573-9.|[3]Benedito R B, et al. Perillyl alcohol: antinociceptive effects and histopathological analysis in rodent brains. Natural Product Communications, 2017, 12 (9) : 1934578X1701200902.|[4]Chen TC, et al. Preclinical development and clinical use of perillyl alcohol for chemoprevention and cancer therapy. Am J Cancer Res. 2015 Apr 15;5 (5) :1580-93.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 1

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