Products for Research Use Only
RegisterLogin

Nrf2 Rabbit Polyclonal Antibody

CAT: 0992-ER1706-41Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3Product image 4Product image 5Product image 6
1 / 6
CAT#:0992-ER1706-41Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The NF-E2 DNA binding protein is composed of two subunits, p45 and MafK. It regulates expression of globin genes in developing erythroid cells through interaction with Maf recognition elements (Mares). A family of NF-E2- related proteins, which are collectively known as the Cap 'n' collar (CNC) family and include Nrf1 (also designated TCF11), Nrf2 and Nrf3, are bZIP transcription factors that heterodimerize with Maf proteins to bind Mare sequences. The Nrf proteins also bind the antioxidant response element (ARE) and are implicated in the regulation of detoxification enzymes and the oxidative stress response. They do so by heterodimerizing with Jun family members (c-Jun, Jun B and Jun D) to activate gene expression, specifically the detoxifying enzyme NQO1. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from its repressor protein, Keap1.
CAS Number
9007-83-4
Product Name Alternative
erythroid derived 2 antibody HEBP1 antibody like 2 antibody NF E2 related factor 2 antibody NF-E2-related factor 2 antibody NF2L2_HUMAN antibody NFE2 related factor 2 antibody NFE2-related factor 2 antibody Nfe2l2 antibody Nrf 2 antibody NRF2 antibody Nuclear factor (erythroid derived 2) like 2 antibody Nuclear factor antibody nuclear factor erythroid 2 like 2 antibody Nuclear factor erythroid 2 related factor 2 antibody Nuclear factor erythroid 2-related factor 2 antibody Nuclear factor erythroid derived 2 like 2 antibody
Abbreviation
NF-E2-related factor 2,NFE2-related factor 2,
Swiss Prot
Q16236 Human, Q60795 Mouse, O54968 Rat
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within N-terminal human Nrf2.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P, FC
Positive Control
Hela cell lysates, HCT116 cell lysates, HCT 116 cells treated with 10 μM MG-132 for 6 hours, MEF cells treated with 10 μM MG-132 for 6 hours, rat brain tissue, human lung tissue, mouse fallopian tubes tissue, human spleen tissue, human uterus tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:100 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.5% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 68 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
HA72$3302Nrf2 Recombinant Rabbit monoclonal Antibody
HA751401Nrf2 Recombinant Rabbit monoclonal Antibody
R1312-8Anti-Nrf2 Antibody
HA750142Phospho-Nrf2 (S40) Recombinant Rabbit monoclonal Antibody
HA721432Nrf2 Recombinant Rabbit Monoclonal Antibody [JE30-14]
ET1608-28Phospho-Nrf2 (S40) Recombinant Rabbit Monoclonal Antibody [SU0334]
ET1608-28TRAnti-Phospho-Nrf2 (S40) Antibody [SU0334]
HA500570Nrf3 Rabbit polyclonal Antibody
ER1902-26GM648 Rabbit Polyclonal Antibody
ER1706-80CD4 Rabbit Polyclonal Antibody

Alternative Products

CatalogName
MBS8597032-01Nrf2 Rabbit Polyclonal Antibody
NBP1-32822Rabbit Polyclonal Nrf2 Antibody
ES8568-01Nrf2 Rabbit Rabbit Polyclonal Antibody
GTR17836833Nrf2 Rabbit Polyclonal Antibody (RBITC)
GTR18310577Nrf2 Rabbit Polyclonal Antibody (FITC)
GTR17784674Nrf2 Rabbit Polyclonal Antibody (AP)
TA379080Nrf2 (NFE2L2) Rabbit Polyclonal Antibody
GTR18269441Nrf2 Rabbit Polyclonal Antibody (BF405)
GTR18269440Nrf2 Rabbit Polyclonal Antibody (BF488)
GTR18269439Nrf2 Rabbit Polyclonal Antibody (BF555)

Popular Products