Pinaverium bromide-d4

• UNSPSC Description:

  Pinaverium bromide-d4 is deuterium labeled Pinaverium bromide. Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients[1].

• Target Antigen:

  Calcium Channel; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling;Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1(C)[C@@H]2CC[C@H](CCOC([2H])([2H])C([2H])([2H])[N+]3(CC4=CC(OC)=C(OC)C=C4Br)CCOCC3)[C@H]1C2.[Br-]

• Molecular Weight:

  595.44

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Dai Y, et al. Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats. World J Gastroenterol. 2003 Mar;9(3):557-61.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported