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Pinaverium bromide

CAT: 0804-HY-111613-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111613-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients[1].
CAS Number
53251-94-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Pinaverium_bromide.html
Purity
99.73
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1(C)C2CCC(CCOCC[N+]3(CC4=CC(OC)=C(OC)C=C4Br)CCOCC3)C1C2.[Br-]
Molecular Formula
C26H41Br2NO4
Molecular Weight
591.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Dai Y, et al. Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats. World J Gastroenterol. 2003 Mar;9 (3) :557-61.|[2]Chen X, et al. Pinaverium Bromide Attenuates Lipopolysaccharide-Induced Excessive Systemic Inflammation via Inhibiting Neutrophil Priming. J Immunol. 2021 Apr 15;206 (8) :1858-1865. |[3]Dai Y, et al. Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats. World J Gastroenterol. 2003 Mar;9 (3) :557-61.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
L-type calcium channel

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