1-Hydroxypyrene-d9

• UNSPSC Description:

  1-Hydroxypyrene-d9 is the deuterium labeled 1-Hydroxypyrene[1]. 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes[2].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Purity:

  99.95

• Solubility:

  DMSO : 50 mg/mL (ultrasonic;warming)

• Smiles:

  OC1=C2C3=C4C(C([2H])=C2[2H])=C([2H])C([2H])=C([2H])C4=C([2H])C([2H])=C3C([2H])=C1[2H]

• Molecular Weight:

  227.31

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Fernando Freitas, et al. Urinary 1-hydroxypyrene Is Associated With Oxidative Stress and Inflammatory Biomarkers in Acute Myocardial Infarction. Int J Environ Res Public Health

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  132603-37-3