Caspase 1 (Interleukin-1Beta Converting Enzyme, ICE) (PE)

• NCBI Gene ID:

  834

• Reactivity:

  Human

• Storage Conditions:

  Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

• Specificity:

  Recognizes the p20 subunit of Caspase 1 and recognizes the P45 proenzyme (~45kD) and the p20 subunit (~20kD) of the reduced, human Caspase 1 isoform. May cross-react with Caspase 5 due to 92% sequence homology. Species sequence homology: mouse, rat, canine, porcine and feline (92% sequence homology).

• Other Gene Names:

  [CASP1; CASP1; ICE; P45; IL1BC; IL1BC; IL1BCE; CASP-1; IL-1BC; ICE]

• Short Name:

  [Caspase 1]

• Other Product Names:

  [caspase-1 isoform beta; Caspase-1; caspase-1; caspase 1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45]

• NCBI GI Number:

  4502573

• NCBI Accession Number:

  NP_001214

• NCBI GB Accession Number:

  NM_001223

• Uniprot Accession Number:

  P29466