Caspase 1 (Interleukin-1Beta Converting Enzyme, ICE) (Biotin)

• NCBI Gene ID:

  834

• Reactivity:

  Human

• Storage Conditions:

  Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

• Specificity:

  Recognizes the p20 subunit of Caspase 1 and recognizes the P45 proenzyme (~45kD) and the p20 subunit (~20kD) of the reduced, human Caspase 1 isoform. May cross-react with Caspase 5 due to 92% sequence homology. Species sequence homology: mouse, rat, canine, porcine and feline (92% sequence homology).

• Other Gene Names:

  [CASP1; CASP1; ICE; P45; IL1BC; IL1BC; IL1BCE; CASP-1; IL-1BC; ICE]

• Short Name:

  [Caspase 1]

• Other Product Names:

  [caspase-1 isoform beta; Caspase-1; caspase-1; caspase 1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45]

• NCBI GI Number:

  4502573

• NCBI Accession Number:

  NP_001214

• NCBI GB Accession Number:

  NM_001223

• Uniprot Accession Number:

  P29466