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N-Acetyl-Leukotriene E4

CAT: 0804-HY-131395-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-131395-01Size:25 µg
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Description
N-Acetyl-Leukotriene E4 (N-Acetyl-LTE4) is a metabolite of Leukotriene E4 (LTE4) , which is detected in bile and urine[1]. N-Acetyl-Leukotriene E4 produces a vasoconstriction in the mesenteric vessels which led to reduction of blood flow to the gut[2].
CAS Number
80115-95-3
Product Name Alternative
N-Acetyl-LTE4
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/n-acetyl-leukotriene-e4.html
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](NC(C)=O)C(O)=O)[C@@H](O)CCCC(O)=O
Molecular Formula
C25H39NO6S
Molecular Weight
481.65
References & Citations
[1]Uemura M, et al., Cysteinyl leukotrienes in the urine of patients with liver diseases. Hepatology. 1994 Oct;20 (4 Pt 1) :804-12.|[2]Siren AL, et al., N-acetyl-leukotriene E4 is a potent constrictor of rat mesenteric vessels. Eur J Pharmacol. 1988 Feb 9;146 (2-3) :331-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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