LRP5 rabbit pAb
CAT:
855-ES15106-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
LRP5 rabbit pAb
- Description: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
- Gene ID: 4041
- UniProt: O75197
- Cellular Locus: Membrane ; Single-pass type I membrane protein. Endoplasmic reticulum. Chaperoned to the plasma membrane by MESD..
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: Synthesized peptide derived from human LRP5 AA range: 1047-1097
- Clonality: Polyclonal
- Validated Applications: WB
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1：500-2000
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.