Trastuzumab (anti-HER2)
CAT:
804-HY-P9907A-03
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Trastuzumab (anti-HER2)
- CAS Number: 9007-83-4
- UNSPSC Description: Trastuzumab (PBS) is a humanized IgG1 monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab (PBS) has the potential for HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer research.
- Target Antigen: ADC Antibody; EGFR
- Type: Inhibitory Antibodies
- Related Pathways: Antibody-drug Conjugate/ADC Related;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/trastuzumab-anti-her2.html
- Purity: 99.72
- Solubility: 10 mM in DMSO
- Smiles: [Trastuzumab (anti-HER2)]
- References & Citations: [1]Sliwkowski MX, et al. Nonclinical studies addressing the mechanism of action of trastuzumab. Semin Oncol. 1999 Aug;26(4 Suppl 12):60-70.|[2]Hudis CA, et al. Trastuzumab--mechanism of action and use in clinical practice. N Engl J Med. 2007 Jul 5;357(1):39-51.|[3]Barok M, et al. Trastuzumab causes antibody-dependent cellular cytotoxicity-mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance. Mol Cancer Ther. 2007 Jul;6(7):2065-72.
- Shipping Conditions: Dry Ice
- Storage Conditions: Store at -80°C for 2 years
- Clinical Information: Phase 4