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Levomepromazine (Standard)

CAT: 0804-HY-B1693R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1693R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Levomepromazine (Standard) is the analytical standard of Levomepromazine. This product is intended for research and analytical applications. Levomepromazine (Methotrimeprazine) is an orally active antipsychotic compound and Ca2+ release inducer. Levomepromazine inhibits SERCA pump and induces an increase in cytoplasmic Ca2+ levels. Levomepromazine has antagonistic effects on a variety of neurotransmitter receptors, including dopamine, cholinergic, serotonin, and histamine receptors. Levomepromazine can induce adaptive ER stress and autophagy. In addition, Levomepromazine has antiviral, anti-inflammatory, neuroprotective and analgesic, sedative and anti-injurious activities. Levomepromazine can be used in the study psychiatric disorders and relieving nausea and vomiting[1][2][3].
CAS Number
60-99-1
Product Name Alternative
Methotrimeprazine (Standard)
UNSPSC
12352005
Target
5-HT Receptor; Autophagy; Calcium Channel; Dopamine Receptor; Enterovirus; Histamine Receptor; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Autophagy; GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/levomepromazine-standard.html
Smiles
COC1=CC=C2SC3=C(N(C2=C1)C[C@@H](CN(C)C)C)C=CC=C3
Molecular Formula
C19H24N2OS
Molecular Weight
328.47
References & Citations
[1]Cox L, et al. Levomepromazine for nausea and vomiting in palliative care. Cochrane Database Syst Rev. 2015 Nov 2; (11) :CD009420.|[2]Sivaraman P, et al. Levomepromazine for schizophrenia. Cochrane Database Syst Rev. 2010 Oct 6; (10) :CD007779.|[3]Prajapat SK, et al. Methotrimeprazine is a neuroprotective antiviral in JEV infection via adaptive ER stress and autophagy. EMBO Mol Med. 2024 Jan;16 (1) :185-217.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Launched