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NOTCH3 polyclonal antibody

CAT: 0013-GTR18044073-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18044073-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal antibody to NOTCH3
Product Name Alternative
Neurogenic locus notch homolog protein 3; Notch 3; NOTCH3
UniProt
Q9UM47
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human NOTCH3.
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB: 1:500-1:1000
Form
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
~ 244 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · Q9UM47

Neurogenic locus notch homolog protein 3

NOTC3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UM47
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 3
EC number
—
Processing
Precursor
Secondary accessions
Q9UEB3, Q9UPL3, Q9Y6L8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Cellular component

Cell membraneMembraneNucleus

Biological process

DifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Disease

Disease variant

PTM

Disulfide bondGlycoproteinMethylationPhosphoprotein

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