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Epibetulinic acid

CAT: 0804-HY-N0223Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0223Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
CAS Number
38736-77-5
UNSPSC
12352211
Target
NO Synthase; Prostaglandin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/epibetulinic-acid.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1(C)[C@H](O)CC[C@]2(C)[C@@]3([H])CC[C@]4([H])[C@@]5([H])[C@H](C(C)=C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
Molecular Formula
C30H48O3
Molecular Weight
456.70
References & Citations
[1]Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14 (5) :1573-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
EP

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