Heptaplatin

CAT: 0804-HY-106588-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-106588-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Heptaplatin (SKI 2053R) is a platinum derivative with anticancer activity against various cancer cell lines, including cisplatin-resistant tumor cell lines. SKI-2053R is active in the research of gastric adenocarcinoma and has favorable toxicity profiles[1].

CAS Number

146665-77-2

Product Name Alternative

SKI 2053R

UNSPSC

12352300

Hazard Statement

H302-H315-H319-H335

Target

DNA Alkylator/Crosslinker

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/heptaplatin.html

Solubility

10 mM in DMSO

Smiles

O=C(O[Pt]([NH2]C1)(O2)[NH2]C[C@@]3([H])OC(O[C@]13[H])C(C)C)CC2=O

Molecular Formula

C11H20N2O6Pt

Molecular Weight

471.36

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Kim NK, et al. Phase II clinical trial of SKI-2053R, a new platinum analog, in the treatment of patients with advanced gastric adenocarcinoma. Cancer. 1999;86 (7) :1109-1115.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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