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Tangeretin

CAT: 0804-HY-N0133-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0133-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor.
CAS Number
481-53-8
Product Name Alternative
Tangeritin; NSC53909; NSC618905
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Notch
Type
Natural Products
Related Pathways
Apoptosis; Neuronal Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Tangeretin.html
Purity
99.36
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(OC)C=C2)OC3=C(OC)C(OC)=C(OC)C(OC)=C13
Molecular Formula
C20H20O7
Molecular Weight
372.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang X, et al. Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. Oncol Rep. 2015 Jul;34 (1) :302-10.|[2]Xu JJ, et al. Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo. J Agric Food Chem. 2015 Nov 4;63 (43) :9520-7.|[3]Hagenlocher Y, et al. Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells. Eur J Nutr. 2017 Jun;56 (4) :1609-1620.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
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