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Sucralose-d6

CAT: 0804-HY-N0614SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0614SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sucralose-d6 is deuterium labeled Sucralose. Sucralose? (E955; Trichlorosucrose) is a?non-nutritive?artificial?sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents[1][2].
CAS Number
1459161-55-7
Product Name Alternative
E955-d6; Trichlorosucrose-d6
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.11
Solubility
10 mM in DMSO
Smiles
Cl[C@@H]1[C@@H]([C@H]([C@H](O[C@@H]1C([2H])(O)[2H])O[C@]2([C@H]([C@@H]([C@H](O2)C([2H])(Cl)[2H])O)O)C([2H])(Cl)[2H])O)O
Molecular Formula
C12H13D6Cl3O8
Molecular Weight
403.67
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]M S, et al. Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice. Int J Occup Environ Health. 2016 Jan;22 (1) :7-17.|[3]Nabanita Kundu, et al. Sucralose promotes accumulation of reactive oxygen species (ROS) and adipogenesis in mesenchymal stromal cells. Stem Cell Res Ther. 2020 Jun 26;11 (1) :250.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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