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Trans-VUF25471

CAT: 0804-HY-161414Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161414Size:1 Each
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Description
Trans-VUF25471 (Compound trans-3e) is a photoswitchable ACKR3 agonist. trans-VUF25471 binds and activates ACKR3 at 10-fold lower concentrations compared to its cis-isomer[1].
UNSPSC
12352005
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trans-vuf25471.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C)(C)C)C1CCN(CC2=CC=CC(/N=N/C3=CC=C(F)C=C3)=C2)CC1
Molecular Formula
C23H29FN4O
Molecular Weight
396.50
References & Citations
[1]Sophie Bérenger, et al. Design, synthesis and pharmacological characterization of the first photoswitchable small-molecule agonist for the Atypical Chemokine Receptor 3.bioRxiv 2024.03.20.585914
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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