Rubiadin-1-methyl ether

Rubiadin-1-methyl ether

• CAS Number: 7460-43-7
• UNSPSC Description: Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].
• Target Antigen: NF-κB
• Type: Natural Products
• Related Pathways: NF-κB
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/rubiadin-1-methyl-ether.html
• Purity: 98.89
• Solubility: DMSO : ≥ 125 mg/mL
• Smiles: O=C1C2=C(C=CC=C2)C(C3=CC(O)=C(C)C(OC)=C13)=O
• Molecular Weight: 268.26
• References & Citations: [1]He YQ, et al. Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathway. Biochem Biophys Res Commun. 2018 Dec 2;506(4):927-931.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported