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APP polyclonal antibody

CAT: 0013-GTR18039682-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18039682-02Size:100 µL
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Description
Rabbit polyclonal antibody to APP
Product Name Alternative
Anti-Amyloid beta A4 protein antibody, anti-ABPP antibody, anti-APPI antibody, anti-Short name=APP antibody, anti-Alzheimer disease amyloid protein antibody, anti-Cerebral vascular amyloid peptide antibody, anti-Short name=CVAP antibody, anti-PreA4 antibody, anti-Protease nexin-II antibody, anti-Short name=PN-II antibody, anti-N-APP antibody, anti-Soluble APP-alpha antibody, anti-Short name=S-APP-alpha antibody, anti-Soluble APP-beta antibody, anti-Short name=S-APP-beta antibody, anti-Beta-amyloid protein 42 antibody, anti-Beta-APP42 antibody, anti-Beta-amyloid protein 40 antibody, anti-Beta-APP40 antibody, anti-P3 (42) antibody, anti-P3 (40) antibody, anti-Gamma-secretase C-terminal fragment 59 antibody, anti-Amyloid intracellular domain 59 antibody, anti-Short name=AICD-59 antibody, anti-Short name=AID (59) antibody, anti-Gamma-CTF (59) antibody, anti-Gamma-secretase C-terminal fragment 57 antibody, anti-Amyloid intracellular domain 57 antibody, anti-Short name=AICD-57 antibody, anti-Short name=AID (57) antibody, anti-Gamma-CTF (57) antibody, anti-Gamma-secretase C-terminal fragment 50 antibody, anti-Amyloid intracellular domain 50 antibody, anti-AICD-50 antibody, anti-AID (50) antibody, anti-Gamma-CTF (50) antibody, anti-APP antibody, anti-A4 antibody, anti-AD antibody, anti-Amyloid- beta antibody, anti-Amyloid beta antibody, anti-Amyloid beta antibody, anti-beta Amyloid antibody, anti-beta Amyloid antibody, anti-A beta antibody
UniProt
P05067
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human APP (NP_000475.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB: 1:500-1:2000, IHC-P: 1:50-1:200
Form
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
100-140KDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IF
Host or Source
Rabbit
Preservative
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · P05067

Amyloid-beta precursor protein

A4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05067
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
APP
EC number
—
Processing
Precursor
Secondary accessions
B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q6GSC0, Q8WZ99, Q9BT38, Q9UC33, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

AmyloidCell membraneCell projectionCoated pitCytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Biological process

ApoptosisCell adhesionEndocytosisNotch signaling pathway

Ligand

CopperIronMetal-bindingZinc

PTM

Disulfide bondGlycoproteinIsopeptide bondOxidationPhosphoproteinProteoglycanSulfationUbl conjugation

Molecular function

Heparin-bindingProtease inhibitorSerine protease inhibitor

Domain

SignalTransmembraneTransmembrane helix

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