Dodecylphosphocholine

• Description:

  Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins[1][2].

• UNSPSC:

  12352211

• Hazard Statement:

  H315, H317, H319, H335, H360

• Target:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dodecylphosphocholine.html

• Purity:

  99.97

• Solubility:

  DMSO : 32.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

• Smiles:

  O=P ([O-]) (OCC[N+] (C) (C) C) OCCCCCCCCCCCC

• Molecular Formula:

  C17H38NO4P

• Molecular Weight:

  351.46

• Precautions:

  H315, H317, H319, H335, H360

• References & Citations:

  [1]de Haas GH, Dijkman R, Ransac S, Verger R. Competitive inhibition of lipolytic enzymes. IV. Structural details of acylamino phospholipid analogues important for the potent inhibitory effects on pancreatic phospholipase A2. Biochim Biophys Acta. 1990;1046 (3) :249-257. |[2]François Dehez, et al. Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity. Biophys J. 2017 Dec 5;113 (11) :2311-2315.|[3]Sarah D Cady, et al. Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. J Am Chem Soc. 2011 Mar 30;133 (12) :4274-84.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  29557-51-5