Menthofuran-13C2
CAT:
804-HY-N9484S
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Menthofuran-13C2
- UNSPSC Description: Menthofuran-13C2 is 13C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice[1][2][3].
- Target Antigen: Drug Metabolite; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: Metabolic Enzyme/Protease;Others
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/menthofuran-13c2.html
- Solubility: 10 mM in DMSO
- Smiles: CC(C1)CCC2=C1O[13CH]=C2[13CH3]
- Molecular Weight: 152.20
- References & Citations: [1]Gordon WP, et al. The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran. Drug Metab Dispos. 1987 Sep-Oct;15(5):589-94. |[2]Mahmoud SS, et al. Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14481-6. |[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported