Alginic acid

Alginic acid

• CAS Number: 9005-32-7
• UNSPSC Description: Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties[1][2][3].
• Target Antigen: Apoptosis; Autophagy; Endogenous Metabolite; Histamine Receptor
• Type: Natural Products
• Related Pathways: Apoptosis;Autophagy;GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Endocrinology; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/alginic-acid.html
• Purity: 97.0
• Solubility: H2O : 3.03 mg/mL (ultrasonic;adjust pH to 12 with 1M NaOH)
• Smiles: [C@@H]1([C@@H]([C@@H](C(=O)O)O[C@H]([C@H]1O)O[C@H]2[C@@H]([C@@H]([C@H](O[C@H]3[C@@H]([C@@H]([C@H](O)O[C@H]3C(=O)O)O)O)O[C@H]2C(=O)O)O)O)O)O
• Molecular Weight: 546.39
• References & Citations: [1]Guo X, et al. Structures, properties and application of alginic acid: A review. Int J Biol Macromol. 2020;162:618-628. |[2]Cui J, et al. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Toxicology. 2022;467:153099.|[3]Jeong HJ, et al. Alginic acid has anti-anaphylactic effects and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation. Clin Exp Allergy. 2006;36(6):785-794.
• Shipping Conditions: Room Temperature
• Storage Conditions: Store at room temperature 3 years
• Clinical Information: No Development Reported